The splenic M O showed auxetic growth, and the number of lysosomes in MO cytoplasm and the gibbosity on the M O surface increased evidently, and the number of lymphocytes also obviously raised in normal rats through electron microscope ( EMS) examination. 电镜观察发现,蝉拟青霉使正常大鼠脾Mφ体积增大,胞质内溶酶体增多,细胞表面可见粗而短的突起,淋巴细胞数量增多。